Extracellular fluid and intracellular fluid

The main difference between intercellular and extracellular fluid is that intracellular fluid is the liquid found inside the cell whereas extracellular fluid refers to all the body fluids outside the cell. The intracellular fluid is also known as the cytosol of the cell, comprising a complex mixture of organelles, proteins, and ions This video Extracellular Fluid (ECF) and Intracellular Fluid (ICF): Water & Sodium Pathophysiology is part of the Lecturio course Nephrology: Foundations.. Extracellular fluid present outside the cell and intracellular fluid present inside the. Key Differences between Intracellular Fluids and Extracellular Fluids. Intracellular fluid is fluid within the cell whereas extracellular fluid is a fluid located outside the cell. Intracellular fluid is composed of water and dissolved proteins and solutes whereas extracellular fluid is composed of blood plasma, interstitial fluid, lymph and transcellular fluid

The intracellular fluid (ICF) is the fluid within cells. The interstitial fluid (IF) is part of the extracellular fluid (ECF) between the cells. Blood plasma is the second part of the ECF. Materials travel between cells and the plasma in capillaries through the IF Extracellular: interstitial and plasma Distribution of electrolytes is similar in plasma and interstitial fluids and inside the cells. The difference in distribution is negligible. In the interstitial fluid, there are virtually no proteins. If there are any proteins (albumin for example), they pass to the lymphatic system The distribution of fluid throughout the body can be broken down into two general categories: intracellular fluid and extracellular fluid. Intracellular fluid is approximately 40% of the total body weight. It is the total space within cells primarily defined as the cytoplasm of cells. In general, intracellular fluids are stable and do not.

Difference Between Intracellular and Extracellular Fluid

• Extracellular fluid (ECF) or extracellular fluid volume (ECFV) usually denotes all the body fluid that is outside of the cells. The extracellular fluid can be divided into two major subcompartments: interstitial fluid and blood plasma. The extracellular fluid also includes the transcellular fluid; this makes up only about 2.5% of the ECF
• Intracellular fluid is often referred to as cytosol when discussing cellular functions. The cytosol and the organelles and molecules contained within are referred to collectively as the cytoplasm. The opposite of the intracellular fluid is the extracellular fluid, which exists on the outside of the cells in the extracellular compartment of the body. Many cellular mechanisms and enzymes work to move products and wastes from the intracellular fluid to the extracellular fluid, while at the same.
• Potasium is the principal intra-cellular. cation. The intracellular fluid contains large amount of potassium and phosphate ions. and proteins. It contains moderate quantities of sodium and sulphate ions. The intracellular. fluid contains only small quantities of sodium and chloride ions and almost no calcium ions. Extracellular Fluid (ECF
• The key difference is in the name. Intracellular fluid is the fluid within a cell, such as the cytoplasm. Extracellular fluid is outside of the cell, which there are numerous types in connective tissue. Intracellular fluid is generally filled with the proteins and molecules that characterize the function of the cell

Intracellular Fluid. Intracellular fluid (ICF) contains predominantly K+, while extracellular fluid (ECF) contains predominantly Na+ (Table 2.1), and it is this difference in ionic concentration between ICF and ECF that, first, allows the generation of the RMP and, second, provides the battery that drives the action potential Intracellular fluid (ICF) contains predominantly K+, while extracellular fluid (ECF) contains predominantly Na+ (Table 2.1), and it is this difference in ionic concentration between ICF and ECF that, first, allows the generation of the RMP and, second, provides the battery that drives the action potential Intracellular fluid contains water and dissolved solutes and proteins. The solutes are electrolytes, which help keep our body functioning properly. An electrolyte is an element or compound that, when dissolved in fluid, breaks up into ions. Also Know, what are intracellular ions? Sodium chloride is found mostly in extracellular fluid, while.

Extracellular Fluid and Intracellular Fluid: Water

In this video we discuss what is the extracellular matrix and what is interstitial fluid. We also cover some of the functions of the extracellular matrix as.. The key difference between intracellular and extracellular fluids is that the fluid inside the cell is intracellular fluid, while the fluid outside the cell is extracellular fluid. A cell is the basic structural and functional unit of life. A cell membrane surrounds the cell, separating the cell interior and external environment The body's fluid separates into two main compartments: Intracellular fluid volume (ICFV) and extracellular fluid volume (ECFV). Of the 42L of water found in the body, two-thirds of it is within the intracellular fluid (ICF) space, which equates to 28L

Extracellular and Intracellular Fluids The Biology Note

The Body Fluid Compartments : Extracellular and Intracellular Fluids: Interstitial Fluid and Edema Body Fluids and The Kidneys 3. The maintenance of a relatively constant volume and a stable composition of the body fluids is essential for homeostasis Fluid Intake and Output are Balanced During Steady-State Conditions 4 It differs from intracellular fluid (fluid within the cells) in that it generally has a high concentration of sodium and low concentration of potassium, while intracellular fluid is high in potassium and low in sodium. The fluid is often secreted by cells to provide a constant environment for cellular operations In cell biology, extracellular fluid (ECF) denotes all body fluid outside the cells of any multicellular organism. Total body water in healthy adults is about 60% (range 45 to 75%) of total body weight; [citation needed] women and the obese typically have a lower percentage than lean men. Extracellular fluid makes up about one-third of body fluid, the remaining two-thirds is intracellular. In dehydration, fluid from the extracellular compartment is depleted first, followed by fluid from the intracellular space. Fluid loss from the intracellular space results in cellular shrinkage and metabolic dysfunction. Dehydration occurs because of decreased water intake, increased fluid loss, or both

The fluid inside the cells is called intracellular fluid (IFC) and the fluid outside the cells is called the extracellular fluid (EFC). These two fluids are separated by a semipermeable membrane that surrounds the cell The most obvious difference between these two fluids is that one is inside of the cell and the other is outside of the cell. Extracellular fluid accounts for about 1/3 of the fluid in the human body and has more ionic components than intracellular.. In response to transcutaneous electrical vagus stimulation, changes occur in body fluids i.e. fluid shifts in extracellular and intracellular media that can be assessed by Cole parameters R e and R i before and after stimulus, by measuring single side impedance spectroscopy (from 3 kHz to 1 MHz) between wrist and ankle. Following a resting.

Intracellular Fluids vs

• The best way to measure extracellular water is to divide your extracellular water by your total body water (ECW/TBW). The number you receive will represent the ratio of extracellular water to your total body water. Between 20 and 85 years old, a normal ratio is generally between 0.36 to 0.39. In certain diseased states, the ratio will exceed 0.40
• except the proteins. Therefore, the extracellular fluids are constantly mixing, so the plasma and interstitial fluids have about the same composition except for proteins, which have a higher concentration in the plasma. BLOOD VOLUME Blood contains both extracellular fluid (the fluid in plasma) and intracellular fluid (the fluid in the red blood.
• The intercellular fluid compartment (ICF) occupies nearly two-thirds of all water in the organism and flows within the body cells. In contrast to ICF, the extracellular fluid compartment (ECF) forms the remaining one-third of the water. It is located in the bones, body tissues, and vascular systems, including blood and lymph

the kidneys and glands, pericardial, peritoneal, synovial, cerebrospinal fluid. All the body fluids intracellular, extracellular (interstitial, plasma or vascular) contains electrolytes. The electrolyte concentration varies in these fluids, it is 45-50% of body weight in intercellular fluid, interstitial fluid makes 12-15 % and plasma makes 4-5 Distinguish between intracellular and extracellular fluids; Key Points. The intracellular fluid of the cytosol or intracellular fluid (or cytoplasmic matrix) is the liquid found inside cells. The cytosol is a complex mixture of substances that include proteins, ions, and organelles dissolved in water Extracellular fluid comprises 27% body weight while Intracellular fluid comprises 33% body weight. Extracellular fluid has a lack of proteins and amino acids while the presence of proteins and amino acids is a feature of I ntracellular fluid. Extracellular fluid has more concentration of ions compared to Intracellular fluid The intracellular fluid is separated from the extracel-lular fluid by a cell membrane that is highly permeable to water but not to most of the electrolytes in the body. In contrast to the extracellular fluid, the intracellu-lar fluid contains only small quantities of sodium and chloride ions and almost no calcium ions

Body Fluids and Fluid Compartments Anatomy and Physiology I

1. The purpose of this study was to test the validity of a multiple frequency bioimpedance spectroscopy (BIS) technique that estimates extracellular fluid volume (ECV), intracellular fluid volume (ICV), and total body water (TBW). Thirteen healthy males (mean +/- SD: age, 23 +/- 3 yr; body mass, 80.6 +
2. Of this 60%, 40% (28 liters) is contained within the cells (intracellular fluid, ICL) and 20% (14 liters) in the extracellular spaces.Due to the small volume of the so-called special compartments, it is customary to consider the extracellular fluid as consisting only of interstitial fluid and plasma
3. The intracellular fluid compartment contains most of the water in the body (~67% of total). Interstitial fluid contains ~25% of the total body water. Plasma is the smallest fluid compartment (~8% of total body water). Note that this diagram places focus only on these three major fluid compartments
4. The water in the body can be divided into two compartments: intracellular and extracellular fluid. About 55% of the water is inside cells, and the remainder is outside. The extracellular fluid, or ECF, can in turn be subdivided into plasma, lymphatic fluid, and interstitial fluid, but for now we can lump all the ECF together into one compartment
5. The water is distributed in three main compartments separated from each other by cell membranes. The intracellular compartment is the area within the cell. The extracellular compartment consists of the interstitial area (between and around cells) and the inside of the blood vessels (plasma)

The intracellular fluid is the fluid contained within cells. The extracellular fluid—the fluid outside the cells—is divided into that found within the blood and that found outside the blood; the latter fluid is known as the interstitial fluid. These fluids are not simply water but contain Read Mor Intracellular fluids possess a low concentration of sodium ions but a high concentration of potassium ions. On the other side, there is a high concentration of sodium and a low concentration of potassium in the extracellular fluid. The intracellular fluid contains about 33% body weight of an organism Your Intracellular fluid: Extracellular fluid must remain at the same levels with respect to each other. A healthy fluid distribution has been estimated at a 3:2 ratio of ICW:ECW. If your body water falls out of balance, this can signal changes in your health and body composition. Whether these changes are positive or negative depend on which. Hypertonic fluids have an osmolarity of 375 mOsm/L or higher. The resulting osmotic pressure gradient draws water from the intracellular space, increasing extracellular fluid volume. These fluids are used to replace electrolytes, to treat hypotonic dehydration, and for temporary treatment of circulatory insufficiency and shock Intracellular fluid is the place where most of the fluid in the body is contained. This fluid is located within the cell membrane and contains water, electrolytes and proteins

The pH of the intracellular fluid is 7.4. The cell membrane separates cytosol from extracellular fluid, but can pass through the membrane via specialized channels and pumps during passive and active transport. The concentrations of the other ions in cytosol or intracellular fluid are quite different from those in extracellular fluid Extracellular fluid versus intracellular fluid : the metabolic tide of the cell @inproceedings{Allison2004ExtracellularFV, title={Extracellular fluid versus intracellular fluid : the metabolic tide of the cell}, author={S. Allison}, year={2004} } S. Allison; Published 200 Figure 15.1 Intracellular and Extracellular Compartments . Intracellular fluids (ICF) are found inside cells and are made up of protein, water, electrolytes, and solutes. The most abundant electrolyte in intracellular fluid is potassium. Intracellular fluids are crucial to the body's functioning

Physiology, Body Fluids - StatPearls - NCBI Bookshel

1. To calculate the interstitial (fluid not in the cells and not in the blood) fluid volume, subtract the plasma volume from the extracellular volume. To calculate the intracellular fluid volume subtract the extracellular fluid volume from the total fluid volume
2. Extracellular fluid. fluid outside the cell. Intracellular fluid. fluid within cells. Solution. a uniform mixture of two or more substances. Concentration gradient. difference between high and low concentrations. Diffusion
3. The intracellular fluid (ICF) compartment is the system that includes all fluid enclosed in cells by their plasma membranes. Extracellular fluid (ECF) surrounds all cells in the body. Extracellular fluid has two primary constituents: the fluid component of the blood (called plasma) and the interstitial fluid (IF) that surrounds all cells not in.
4. compartments: the extracellular fluid and the intracellular fluid (Figure 25-1). The extracellular fluid is divided into the interstitial fluid and the blood plasma. There is another small compartment of fluid that is referred to as transcellular fluid. This compartment includes fluid in the synovial, peritoneal, pericardial, an
5. Intracellular fluid contents has some specific structural characteristics: Small volume, on average, about 2 picoliters. Crowded, filled with proteins (20-30% protein by weight). Much of the water is in an adsorbed form. This has specific functional and chemical advantages
6. Some of the different factors that can cause extracellular and intracellular volumes to change markedly are ingestion of water, dehydration, intravenous infusion of different types of solutions, loss of large amounts of fluid from the gastrointestinal tract, and loss of abnormal amounts of fluid by sweating or through the kidneys.. One can calculate both the changes in intracellular and.
7. The combined concentrations of intracellular cations, sodium and potassium, did not differ significantly from the normal. The pattern of weight loss during therapy was partitioned by utilizing the balance data and revealed that, under the conditions of this study, the loss of edema fluid was isotonic and extracellular in composition

Body Fluids Boundless Anatomy and Physiolog

1. g that extracellular fluid volume is 20 per cent of body weight and intracellular fluid volume is 40 per cent of body weight, the following volumes and concentrations can be calculated. Next, we calculate the total milliosmoles added to the extracellular fluid in 2 liters of 3.0 per cent sodium chloride
2. Answer to in which solution is the intracellular fluid. Transcribed image text: In which solution is the intracellular fluid hypertonic compared to the extracellular fluid? Solution 3 Solution 1 Solution 2 H20 H20 H2O H2O Animal cell Solution 1 Solution 2 O Solution
3. If extracellular fluids (ECF) become hypertonic, as compared to the intracellular fluid (ICF), water will move in which direction? asked Dec 12, 2016 in Health Professions by nookie_notes emergency-medical-service
4. extravascular fluid shift, resulting in ECF volume overload [11]. In addition, malnutrition caused by inflammation could deplete body cell mass, which eventually leads to the decrease in intracellular fluid (ICF) volume, and the relative increase in ECF/ICF volume ratio [12, 13]
5. It's outside the cells, but also inside the blood vessels. The rest of the extracellular fluid is known as interstitial fluid, which is all the rest of the fluid within the tissues. So we have intracellular and extracellular. Then the Extracellular fluid is broken down further into intravascular in the vessels or interstitial in the tissues
6. Extracellular fluid [K] is ~4 mEq/L, whereas the intracellular [K] is ~150 mEq/L. Because of the uneven distribution of potassium between the fluid compartments, a relatively small net shift of potassium from the intracellular to the extracellular fluid compartment produces marked increases in plasma potassium
7. The overall effect of drinking too little fluid is a rise in the osmolality of all intracellular and extracellular body fluids and a decrease in the volumes of both intracellular fluid and extracellular fluid (12, 35). Both shrinking and concentration within cells and the reduction in extracellular volume may have health consequences

Intracellular Fluid - Definition and Quiz Biology Dictionar

These extracellular fluids can be found in the eye, joints, and cerebrospinal fluid. In term of total volume, extracellular fluid actually constitutes a much smaller portion of the total body water than intracellular fluid, which exists within each cell of a body. This can be seen in the graph above Extracellular fluid has two primary constituents: the fluid component of the blood (called plasma) and the interstitial fluid (IF) that surrounds all cells not in the blood ( Figure 26.1.2 ). Figure 26.1.2 - Fluid Compartments in the Human Body: The intracellular fluid (ICF) is the fluid within cells. The interstitial fluid (IF) is part of.

Intracellular Fluid And Extracellular Fluid - Sciencewal

The Intracellular Fluid (ICF) refers to the fluid present inside cells and is considered the sum total of the fluid volume in all of the body's cells. The ICF is separated from the Extracellular Fluid (see below) by the plasma membrane of each, individual cell This fluid is distributed within two compartments: intracellular fluid (ICF) and extracellular fluid (ECF). Fluid and electrolyte management in the neurologically-impaired patient During crisis, the dehydration of RBCs can take place, which could be a possible cause of sodium loss from the extracellular fluid into the intracellular fluid

What is the difference between intercellular and

The intracellular compartment contains two-thirds of the total body water and consists of the fluid inside the body's cells. In dehydration, fluid from the extracellular compartment is depleted first, followed by fluid from the intracellular space. Fluid loss from the intracellular space results in cellular shrinkage and metabolic dysfunction Blood: blood is both extracellular and intracellular fluid. HCT (packed red cell volume) is the fraction of the blood composed of red blood cells. True hematocrit is 96% of the measured hematocrit, due to trapped plasma in between RBCs. Osmolar substances in extracellular and intracellular fluids (pg. 294 table 25-2)

Intracellular Fluid - an overview ScienceDirect Topic

-The intracellular concentration is between 60mmol and 100mmol, but only 10mmol are free. -Phosphate is the most abundant intracellular anion. It acts as an important intracellular buffer. - The rest is in the extracellular fluid; in total, no more than 12mmol. -The extracellular concentration is about 1.0mmol/L The total body fluid contained within the cells is 70%. The extracellular fluid makes up the remaining 30% of total body fluid. Question 4: A patient is admitted from the ER with the following findings: heart rate of 120 (thready, weak pulse), 82/64 blood pressure, 20 mL/hr urinary output, and serum sodium level of 155 The cells will lose water and shrink.The hypertonic extracellular fluid will draw water out of the hypotonic intracellular fluid, so the cells will shrink. This is called crenulation. is correct for If a person is severely dehydrated, their extracellular fluids will become hypertonic to the intracellular fluid

Fluid compartments. intracellular fluid, 63%. extracellular fluid, 37%. interstitial fluid. plasma. name this fluid and volume. name this fluid and volume. name this fluid. (80% of ECF) name this fluid. (20% of ECF) It is found inside of the blood If cells with intracellular osmolarity of 300mOsm are placed in a solution of nonpenetrating solutes having an osmolarity of 300 mOsm, they will neither swell nor shrink since the water concentrations in the intra- and extracellular fluid are the same, and the solutes cannot leave or enter. Such solutions are said to be isotonic (Figure 6 - 20), defined as having the same concentration of. Oct 10, 2020 - Diabetic Ketoacidosis (DKA) pathophysiology finally explained with a simplified flowchart, and an easy mneumonic to remember management principles

Intracellular and Extracellular Fluids Are Normally in Osmotic Equilibrium. Despite the different compositions of ICF and ECF, the total solute concentration (osmolality) of these two fluid compartments is normally the same. ICF and ECF are in osmotic equilibrium because of the high water permeability of cell membranes, which does not permit an. The distribution of body water can be broken down into two main compartments which are divided by the cell membrane. These are the intracellular compartment (ICF) and the extracellular compartment (ECF).About of the total body water is intracellular and the remainder extracellular. This equates to 40% of the total body weight as ICF and the remaining 20% as ECF ECF Extracellular fluid ICF Intracellular fluid TBW Total body water Table of other common abbreviations. INTRODUCTION Water, a primary component of body fluids,is the most abundant substance in the body. Water plays a vital role in several physiologic processes such as digestion, absorption and use of nutrients, distribu

Water constitutes approximately 60% of the healthy human body, with the water in the intracellular and extracellular (interstitial fluid and blood plasma) compartments in osmotic equilibrium. Sodium and chloride ions are abundant in extracellular fluid, while in intracellular fluid, these ions are at low levels with a high concentration of potassium ions * The intracellular fluid compartment is the larger compartment and contains approximately two thirds of total body water. The remaining third is contained in the extracellular fluid compartment. Expressed as percentages of body weight, the volumes of total body water, ICF, and ECF ar Total body water (TBW) is about 60% of body weight in men (ranging from about 50% in obese people to 70% in lean people) and about 50% in women. Almost two thirds of TBW is in the intracellular compartment (intracellular fluid, or ICF); the other one third is extracellular (extracellular fluid, or ECF)

In most instances, edema occurs mainly in the extracellular fluid compartment, but it can involve intracellular fluid as well. Intracellular Edema Two conditions are especially prone to cause intracel-lular swelling: (1) depression of the metabolic systems of the tissues, and (2) lack of adequate nutrition to the cells The amount of water in the body varies depending on age, gender, and body build. In nonobese adults, intracellular fluid constitutes approximately 40% of body weight, and extracellular fluid, 20%. 1,4 (See How body fluid is distributed.) Lean body muscle mass is rich in water, while adipose tissue has a lower percentage of water content Fluid and electrolyte balance is a dynamic process that is crucial for life and homeostasis. Fluid occupies almost 60% of the weight of an adult.; Body fluid is located in two fluid compartments: the intracellular space and the extracellular space.; Electrolytes in body fluids are active chemicals or cations that carry positive charges and anions that carry negative charges Intracellular and Extracellular Fluid (1 of 5) Disturbances of body water are associated with corresponding change in electrolytes. If electrolyte concentration changes, there is a corresponding change in body water and vice versa. Body consists of 70% water. Intracellular water (inside cells

The body fluids composed mainly of water and electrolytes as solutes distributed in the intracellular and extracellular (ICF & ECF) compartments. The ICF are fluids found within the cells while the ECF are those outside the cells. The extracellular fluid compartment is further split into interstitial fluid and the blood plasma The extracellular fluid contains large amounts of sodium, chloride and bicarbonate ions, plus nutrients for the cell such as oxygen, glucose, fatty acids and amino acids. The intracellular fluid contains large amounts of potassium, magnesium an 8. COMPOSITION OF BODY FLUIDS CATIONS (mmol/l) Plasma Interstitial Intracellular Na 142 139 14 K 4.2 4.0 140 Ca 1.3 1.2 0 Mg 0.8 0.7 20 ANIONS (mmol/l) Cl 108 108 4.0 HCO3 24.0 28.3 10 Protein 1.2 0.2 4.0 HPO4 2.0 2.0 11. 9 Total body water can be subdivided into two major compartments, intracellular fluid which is fluid inside cells, and extracellular fluid which is fluid outside of cell like in the blood and in the interstitial tissue between cells. Assuming that the total body water is about 60% of their body weight, roughly 2/3 of that, or 40% is intracellular. Extracellular fluid comprises 27% body weight while Intracellular fluid comprises 33% body weight. Extracellular fluid has a lack of proteins and amino acids while the presence of proteins and amino acids is a feature of I ntracellular fluid. Extracellular fluid has more concentration of ions compared to Intracellular fluid

intracellular and extracellular fluids, so this leads to an equilibrium that has to be met. For potassium, it is high in concentration in the intracellular fluid. Therefore, it has to diffuse to th Comparison chart. Intracellular fluid. Extracellular fluid. Carbon dioxide is produced inside it. Contains carbon dioxide and transports it to the various organs. Holds about 67 percent of water inside the human organism. Holds about 33 percent of water inside the human organism. Contains large amounts of potassium, magnesium, and phosphate ions User: why is the intracellular fluid and extracellular fluid seperated. Weegy: Filteration or evaporation.You can also evaporate the water into a tube, then put a cloth with ice in it, to condense the water and only the water in the tube, which drops the water into the beaker During dehydration, the fluid present in the extracellular fluid compartments (EFC) is lost via evaporation due to the effect of increased temperature (as in the case of sweating)

Intracellular fluid contains approximately two-thirds of the body's fluid. Extracellular fluid is further made up of interstitial fluid and intravascular fluid, which is the blood and plasma. 1- 3 Fluid imbalance occurs when there is a deficit or an excess primarily in extracellular fluid. 1 - 6 Table 15-1 provides an overview of fluid. Phosphate is the most abundant intracellular anion. May 1, 2016 - interstitial fluid vs intracellular fluid - Google Search. The plasma has high concentrations of sodium, chloride, and bicarbonate, but lower levels of protein as compared to the ICF. The maintenance of a relatively constant volume and a stable composition of the body fluids is essential for homeostasis Fluid Intake and Output. Intracellular Fluid (ICF) - fluid found in the cells (cytoplasm, nucleoplasm) comprises 60% of all body fluids. Extracellular Fluid (ECF) - all fluids found outside the cells, comprises 40% of all body fluids Interstitial Fluid - 80% of ECF is found in localized areas: lymph, cerebrospinal fluid, synovial fluid, aqueous humor and vitreous body.

It uses the relation between the body fluid and the impedances in a variety of frequencies. A body model can be simplified as a parallel combination of a capacitor and two resistors which represent a cell membrane, Intracellular Fluid (ICF), and Extracellular Fluid (ECF) In healthy adults, fluid distribution between the intracellular water (ICW) and extracellular water (ECW) compartments is tightly regulated9. However, this regulation is impaired in patients with kidney failure, including ESRD and hemodialysis, as a result of the relative excess of ECW, which results in fluid overload10,11. One of the. 2.1.3 Intracellular Fluid . The Intracellular Fluid is composed of at least 10 14 separate tiny cellular packages. The concept of a single united compartment called intracellular fluid is clearly artificial. The ICF compartment is really a virtual compartment considered as the sum of this huge number of discontinuous small collections